This carefully researched herb has garnered an incredible list of verified therapeutic actions
If there was ever a spice that puts existential fear into the bottom line of pharmaceutical companies, it’s turmeric.
Turmeric is one of the most studied herbs in existence today. Its medicinal properties and components (primarily curcumin) have been the subject of over 12,000 published, peer-reviewed biomedical studies.
In fact, GreenMedInfo (GMI) conducted a five-year research project on this sacred plant and revealed over 800 potential preventive and therapeutic applications, as well as 250 distinct beneficial physiological effects.
This comprehensive database of 2,666 NCBI-linked turmeric abstracts can be downloaded in PDF format from GMI’s Turmeric Downloadable Document page.
Given the density of research being done on this remarkable spice, it’s no wonder that a growing number of studies have concluded that it compares favorably to a variety of conventional medications.
Lipitor/atorvastatin (medicine for cholesterol): A 2008 study published in the journal Drugs in R&D found that a standardized preparation of curcuminoids made from turmeric compared favorably to the drug atorvastatin (trade name Lipitor) on endothelial dysfunction, the underlying blood vessel pathology that causes atherosclerosis, in association with reduction of inflammation and oxidative stress in type 2 diabetic patients.
Corticosteroids (steroid drugs): A 1999 study published in the journal Phytotherapy Research found that the primary polyphenol in turmeric, the saffron-colored pigment known as curcumin, compared favorably to steroids in the management of chronic anterior uveitis, a disease inflammatory eye.
A 2008 study published in Critical Care Medicine found that curcumin compared favorably to the corticosteroid dexamethasone in the animal model as an alternative therapy to protect lung transplant-associated injury by down-regulating inflammatory genes.
An earlier 2003 study published in Cancer Letters found that the same drug also compared favorably to dexamethasone in a model of pulmonary ischemia-reperfusion injury.
Prozac/Fluoxetine & Imipramine (antidepressants): A 2011 study published in the journal Acta Poloniae Pharmaceutica found that curcumin compared favorably to both drugs in reducing depressive behavior in an animal model.
Aspirin (blood thinner): A 1986 in vitro and ex vivo study published in the journal Arzneimittelforschung found that curcumin has antiplatelet and prostacyclin-modulating effects compared to aspirin, indicating that it may have value in patients prone to thrombosis. vascular and requiring anti-arthritic treatment.
Anti-inflammatory drugs: A 2004 study published in the journal Oncogene found curcumin (along with resveratrol) to be effective alternatives to the drugs aspirin, ibuprofen, sulindac, phenylbutazone, naproxen, indomethacin, diclofenac, dexamethasone, celecoxib, and tamoxifen to exert anti-inflammatory effects. -inflammatory and anti-inflammatory. -proliferative activity against tumor cells.
Oxaliplatin (chemotherapy drug): A 2007 study published in the International Journal of Cancer found that curcumin compares favorably to oxaliplatin as an antiproliferative agent in colorectal cell lines.
Metformin (diabetes medicine): A 2009 study published in the journal Biochemistry and Biophysical Research Community explored how curcumin might be useful in the treatment of diabetes, finding that it activates AMPK (which increases glucose uptake) and suppresses the expression of gluconeogenic gene (which suppresses glucose production in the liver) in hepatoma cells. . Interestingly, they found that curcumin was 500-100,000 times more potent (in the form known as tetrahydrocurcuminoids) than metformin in activating AMPK and its downstream target, acetyl-CoA carboxylase (ACC ).
Another avenue through which turmeric and its components reveal their remarkable therapeutic properties is in research on drug-resistant and multi-resistant cancers. There are two sections on the GMI site dedicated to researching natural and integrative therapies on these topics, and while there are dozens of substances with demonstrable efficacy against these chemo- and radiation-resistant cancers, curcumin is at the top of both lists.
We found no less than 97 studies indicating that curcumin can induce cell death or sensitize drug-resistant cancer cell lines to conventional treatments.
We identified 28 studies on the ability of curcumin to induce cell death or sensitize multidrug-resistant cancer cell lines to conventional treatments.
Given the strong track record of turmeric (curcumin), having been used both as a food and as a medicine across a wide range of cultures, for thousands of years, a strong case can be made for using curcumin as an alternative drug or adjuvant in cancer. treatment.
Or, better yet, use certified organic (non-irradiated) turmeric daily in lower culinary doses so that heroic doses are not needed later in life after serious illness sets in. “Nutraceuticals” should be the focus of a healthy diet.